GPT-5.5 vs Mistral Medium 3.1

GPT-5.5 is a multimodal large language model released by OpenAI on April 23, 2026, engineered for autonomous, multi-step knowledge work and agentic workflows. It accepts text, images, and code as input, featuring enhanced spatial reasoning and visual grounding to support its computer use capabilities for operating software and navigating UI elements. Built to execute complex workflows end-to-end, the model interprets loosely defined tasks, selects appropriate tools, and performs self-verification with minimal user intervention. It is available in a standard version, a Thinking mode for extended reasoning budgets, and a Pro variant that uses parallel test-time compute for maximum precision on complex tasks.

Co-optimized with NVIDIA for GB200 NVL72 infrastructure, GPT-5.5 delivers per-token latency comparable to its predecessor GPT-5.4 while maintaining a 1-million-token context window. Despite increased capability, the model achieves greater token efficiency in coding and data analysis workflows, often completing tasks with fewer total tokens than previous versions. OpenAI reports a 60% reduction in hallucination rate compared to GPT-5.4, improving reliability for accuracy-sensitive applications. API access is available via the Responses and Chat Completions endpoints at $5 per million input tokens and $30 per million output tokens, double the unit price of GPT-5.4.

Mistral Medium 3.1, released in August 2025 as the mistral-medium-2508 update, is a proprietary frontier model from Mistral AI positioned between smaller open models and high-end closed LLMs. It is multimodal, handling both text and image inputs, with a context window of ~128K tokens.

Compared to Mistral Medium 3.0, the 3.1 release introduces improvements in reasoning, coding, STEM, and enterprise workflows, along with better tone control for conversational and business applications. It is designed for scalable enterprise deployments, including hybrid cloud and on-premises VPC setups. As part of Mistral’s Premier line, Medium 3.1 is a commercial-only offering: while it delivers strong accuracy and performance, trade-offs include higher costs than open-weight models, restricted fine-tuning access, and increased latency/cost for very large contexts.